Therapeutic Effect of Hedera helix Alcoholic Extract Against Cutaneous Leishmaniasis Caused by Leishmania major in Balb/c Mice
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Therapeutic Effect of Hedera helix Alcoholic Extract Against Cutaneous Leishmaniasis Caused by Leishmania major in Balb/c Mice
BACKGROUND Cutaneous leishmaniasis (CL) is common and endemic in many areas of Iran, caused by species of a protozoan parasite belonging to the genus Leishmania. There is not any effective vaccine against leishmaniasis; so, therapy is important for prevention and separation of disease. Herbal extract for treatment of CL is cost-effective, applicable topically to lesions, and can avoid the devel...
متن کاملtherapeutic effect of hedera helix alcoholic extract against cutaneous leishmaniasis caused by leishmania major in balb/c mice
background: cutaneous leishmaniasis (cl) is common and endemic in many areas of iran, caused by species of a protozoan parasite belonging to the genus leishmania. there is not any effective vaccine against leishmaniasis; so, therapy is important for prevention and separation of disease. herbal extract for treatment of cl is cost-effective, applicable topically to lesions, and can avoid the deve...
متن کاملTherapeutic Effect of Scrophularia striata Ethanolic Extract against Localized Cutaneous Leishmaniasis Caused by Leishmania major (MRHO/IR/75/ER)
BACKGROUND We evaluated the effect of the ethanolic extract of Scrophularia striata on the Iranian strain of Leishmania major (MRHO/IR/75/ER) both in vitro and in vivo conditions. METHODS The effective dose (ED) of ethanolic extract of S. striata were determined using MTT assay on the growth of promastigote forms of L. major in axenic culture media. Then, the ED50 of S. striata on mice perito...
متن کاملtherapeutic effect of scrophularia striata ethanolic extract against localized cutaneous leishmaniasis caused by leishmania major (mrho/ir/75/er)
background: we evaluated the effect of the ethanolic extract of scrophularia striata on the iranian strain of leishmania major (mrho/ir/75/er) both in vitro and in vivo conditions methods: the effective dose (ed) of ethanolic extract of s. striata were determined using mtt assay on the growth of promastigote forms of l. major in axenic culture media. then, the ed 50 of s. striata on mice pe...
متن کاملEfficacy of Paromomycin ointment prepared in Iran (Paromo-U) against cutaneous Leishmaniasis caused by Leishmania major in mouse model
Background: Considering the difficulties, adverse effects and unsuitable response to commonly used drugs; it is essential to find an alternative, particularly local treatment for cutaneous leishmaniasis (CL). Objective: Determination of efficacy of topical paromomycin (Paromo-U ointment) against CL caused by L.major in mouse model. Materials and Methods: Skin lesions were created 1 to 3 months ...
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ژورنال
عنوان ژورنال: Jundishapur Journal of Microbiology
سال: 2014
ISSN: 2008-3645,2008-4161
DOI: 10.5812/jjm.9432